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PEDF Has Tumor-Suppressive and Neuroprotective Functions
- 01/12/2012 19:00 PDT
Pigment epithelium-derived factor rapidly suppresses experimental brain metastases and protects the brain from tumor-induced damage, according to a study published in the Jan. 1 issue of Cancer Research.
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Dark Chocolate Inhibits Platelet Function in Smokers
- 01/12/2012 19:00 PDT
In smokers, dark chocolate lowers oxidative stress and has an inhibitory effect on platelet function, according to a study published in the January issue of the Journal of Thrombosis and Haemostasis.
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Erectile Dysfunction Linked to Previous Psoriasis Diagnosis
- 01/12/2012 19:00 PDT
Erectile dysfunction is associated with a previous diagnosis of psoriasis, according to a study published in the January issue of The Journal of Sexual Medicine.
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Foot Tapping Assesses Motor Function in Cervical Myelopathy
- 01/12/2012 19:00 PDT
The foot tapping test can be used to quantitatively assess lower extremity motor function in patients with cervical myelopathy, according to a study published in the Jan. 15 issue of Spine.
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Patients Give High Marks to Ankle Replacement Surgery
- 01/12/2012 19:00 PDT
Patients who undergo Scandinavian Total Ankle Replacement arthroplasty for treatment of end-stage arthritis report significant intermediate to long-term improvement in pain, function, and quality-of-life scores, according to a study published in the Jan. 4 issue of The Journal of Bone & Joint Surgery.
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Site of Blood Collection From IV Does Not Affect Hemolysis Rate
- 01/12/2012 12:00 PDT
No statistically significant difference in the rate of hemolysis is observed when emergency department nurses collect coagulation blood samples directly via catheter hub or via extension tubing connected to the intravenous catheter hub, according to a study published in the January issue of the Journal of Emergency Nursing.
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Novel Anticancer Agents ID'd From NIH Drug Collection
- 01/12/2012 12:00 PDT
Quantitative high-throughput screening of a large pharmaceutical collection can identify novel agents with anticancer activity, according to a study published online Dec. 14 in the Journal of Clinical Endocrinology & Metabolism.
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Stem Cell Therapy Shows Promise for Type 1 Diabetes
- 01/12/2012 12:00 PDT
"Re-educating" lymphocytes from patients with type 1 diabetes through exposure to cord blood-derived multipotent stem cells is safe and may reverse autoimmunity, according to a study published online Jan. 10 in BMC Medicine.
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Parabens Seen in Almost All Breast Mastectomy Samples
- 01/12/2012 12:00 PDT
One or more esters of p-hydroxybenzoic acid (parabens) are seen in 99 percent of post-mastectomy, primary breast cancer tissue samples, and their concentrations vary within and between breasts, according to a study published online Jan. 12 in the Journal of Applied Toxicology.
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APOE Status, Exercise Combo Impact Amyloid Deposition
- 01/12/2012 12:00 PDT
For cognitively normal carriers of APOE ε4, a sedentary lifestyle is associated with an increased risk of amyloid deposition, according to a study published online Jan. 9 in the Archives of Neurology.
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Three Embryos Should Never Be Implanted in IVF
- 01/12/2012 12:00 PDT
The decision to implant one or two embryos in women during in vitro fertilization should account for maternal factors, including age, but three or more embryos should never be implanted, regardless of age, according to a study published online Jan. 12 in The Lancet.
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Change in Bone Scan Index Predicts Prostate CA Survival
- 01/12/2012 12:00 PDT
On-treatment related change in the bone scan index is strongly associated with survival in patients receiving chemotherapy for metastatic prostate cancer, according to a study published online Jan. 9 in the Journal of Clinical Oncology.
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Physical Activity in Work or Leisure Tied to Lower MI Risk
- 01/12/2012 12:00 PDT
Physical activity during work or leisure time is associated with a significantly lower risk of myocardial infarction, according to a multinational study published online Jan. 11 in the European Heart Journal.
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Low Risk of Cardiac Arrest in Marathon Runners
- 01/12/2012 12:00 PDT
While the overall risk of cardiac arrest during a marathon or half-marathon is low, the risk is higher for those participating in marathons than half-marathons and for men than women, particularly for men with underlying hypertrophic cardiomyopathy or atherosclerotic coronary disease, according to a study published in the Jan. 12 issue of the New England Journal of Medicine.
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Gene Variant Identified in Families With Cold Urticaria
- 01/12/2012 12:00 PDT
The PLCG2 gene, which encodes phospholipase Cγ2, has been found to be associated with a dominantly inherited medical condition causing cold urticaria, immunodeficiency, and autoimmunity, according to a study published online Jan. 11 in the New England Journal of Medicine.