New findings from Vanderbilt University Medical Center published in Nutrients

DAVIS, Calif., Dec. 14, 2023 /PRNewswire/ -- A recent study published online in the journal, Nutrients[1], suggests daily tree nut consumption reduces the risk of metabolic syndrome (MetSx) by improving waist circumference, lipid biomarkers, and/or insulin levels, without requiring calorie restriction, in young adults.

In a randomized, parallel arm, dietary intervention study design, researchers at Vanderbilt University Medical Center enrolled 84 men and women, ages 22-36, most of whom were either overweight or obese (BMI 24.5 to 34.9 kg/m2) and had at least one MetSx risk factor at baseline (abdominal obesity, elevated triglycerides, low HDL cholesterol, high blood pressure, or elevated levels of blood glucose). Participants consumed either one ounce of mixed unsalted tree nuts or one ounce of a carbohydrate-rich snack twice daily. Both snacks provided the same number of calories, protein, fiber, and sodium and were part of a 7-day eucaloric weight maintenance menu that repeated throughout the study duration of 16 weeks.

The results showed females who consumed tree nuts snacks had a reduced waist circumference (mean difference: -2.20 ± 0.73 cm, P = 0.004) and a trend toward reduced visceral (intra-abdominal) fat (-5.27 ± 13.05 cm², P = 0.06) compared to those consuming carbohydrate snacks. Males who consumed tree nuts snacks had decreased blood insulin levels (-1.14 ± 1.41 mIU/L, P = 0.05). Both males and females consuming tree nuts snacks saw an effect on triglycerides and TG/HDL ratios (P = 0.04 for both) with TG/HDL ratios reduced ~11% compared to those consuming carbohydrate snacks.

"When we assessed the effect of tree nut snacks on individual MetSx scores (calculated by assigning 1 point for each metabolic syndrome risk factor)," said Principal Investigator, Heidi J. Silver, R.D., M.S., Ph.D., Research Professor of Medicine at Vanderbilt University Medical Center, "we observed a 67% reduction in MetSx score in females and a 42% reduction in MetSx score in males."

Overall prevalence of MetSx, which increases risk for diabetes and cardiovascular diseases, has increased to 21.3% among healthy American young adults, aged 20-39 years.[2] "We know that snacking contributes almost 25% of total daily calories in young adults in the U.S.," explained Dr. Silver. "Substituting typical high carbohydrate snacks with tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) would likely have a positive impact in reducing the risk of metabolic syndrome and its consequences in this age group."

Previous research has shown the beneficial effects of tree nuts in helping to reduce the risk of several chronic diseases including overweight/obesity, diabetes, and heart disease. "With MetSx and its various risk factors on the rise worldwide, this is yet another reason to include tree nuts in your diet," said Maureen Ternus, M.S., R.D.N, Executive Director of the International Tree Nut Council Nutrition Research & Education Foundation (INC NREF). "In 2003, the FDA (in its qualified health claim for nuts and heart disease) recommended that people eat 1.5 ounces of nuts per day—well above current consumption levels. We need to encourage people—especially those Millennials at risk for MetSx—to get their handful of nuts every day."

The International Tree Nut Council Nutrition Research & Education Foundation (INC NREF) is a non-profit, non-governmental organization dedicated to supporting nutrition research and education for consumers and health professionals throughout the world. Members include those associations and organizations that represent the nine tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts). For more information, please visit our website at www.nuthealth.org.

[1] Sumislawski K., Widmer A., Suro R.R., Robles M.E., Lillegard K., Olson D., Koethe J.R., Silver H.J., 2023. Consumption of tree nuts as snacks reduces metabolic syndrome risk in young adults: A randomized trial. Nutrients. 15, 5051. https://doi.org/10.3390/nu15245051

[1] Hirode, G., R.J. Wong, 2020. Trends in the prevalence of metabolic syndrome in the United States, 2011–2016.JAMA 323:2526–2528.

SOURCE International Tree Nut Council Nutrition Research & Education Foundation