The History of Research Into Vaccines for Shingles Medical Education on ReachMD

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Overview
Decades of research have gone into the isolation and refinement of a vaccine for adult shingles, approved in 2006 by the FDA and in use today. Do we now fully understand the mechanism which activates the latent varicella-zoster virus, leading to adult shingles? How did initial isolation, going back more than 30 years, of the vaccine for chicken pox (triggered by the same varicella virus) contribute to the investigations on adult shingles? Host Dr. Mark Nolan Hill discusses these questions and more with Dr. Michael Oxman, professor of medicine and pathology at the University of California, San Diego School of Medicine, and Dr. William Schaffner, professor and chair of preventive medicine and professor of medicine in the department of infectious diseases at Vanderbilt University School of Medicine.

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Overview
Decades of research have gone into the isolation and refinement of a vaccine for adult shingles, approved in 2006 by the FDA and in use today. Do we now fully understand the mechanism which activates the latent varicella-zoster virus, leading to adult shingles? How did initial isolation, going back more than 30 years, of the vaccine for chicken pox (triggered by the same varicella virus) contribute to the investigations on adult shingles? Host Dr. Mark Nolan Hill discusses these questions and more with Dr. Michael Oxman, professor of medicine and pathology at the University of California, San Diego School of Medicine, and Dr. William Schaffner, professor and chair of preventive medicine and professor of medicine in the department of infectious diseases at Vanderbilt University School of Medicine.

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