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Evolving Pathogenic Concepts on Atopic Dermatitis, its Systemic Nature and its Therapeutic Implications

Atopic dermatitis (AD) is the most common and relapsing allergic disease of the skin. Atopic dermatitis (or atopic eczema) is an inflammatory skin ...

Available credits: 0.50

Time to complete: 30 minutes


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  • Overview

    Atopic dermatitis (AD) is the most common and relapsing allergic disease of the skin. Atopic dermatitis (or atopic eczema) is an inflammatory skin condition characterized by pruritis, and often occurring in the skin flexures. The prevalence rate for atopic dermatitis is estimated at up to 25% in children and 2%-3% adults. The diagnosis and management of patients with atopic dermatitis presents challenges along the course of the disease. New findings from scientific research as to the pathophysiology of AD is redefining strategies for its therapeutic management.

  • Disclosure of Conflicts of Interest

    In accordance with ACCME requirements, National Jewish Health has a conflict of interest policy that requires faculty to disclose financial relationships related to the content of their presentations/materials. Any potential conflicts are resolved so that presentations are evidence-based and scientifically balanced.


    Emma Guttman-Yassky, MD, PhD
    Professor of Medicine and Clinical Immunology
    Icahn School of Medicine at Mount Sinai Hospital
    New York, NY

    Financial Disclosure:
    Consulting Fees: AbbVie, Almirall, Anaco, Asana Biosciences, Celgene, Dermira, Eli Lilly, Galderma, Glenmark, Kiowa Kirin, LEO Pharmaceuticals, Medimmune, Mitsubishi Tanabe, Novartis, Pfizer, Regeneron, Sanofi, Stiefel/GlaxoSmithKline, Vitae
    Contracted Research: Celegene, Eli Lilly, LEO Pharma, Medimmune, Novartis, Regeneron

    CME Reviewers:

    Andrea Harshman, MHA, CHCP, CMP-HC
    Director, Office of Professional Education
    National Jewish Health
    Denver, CO

    Financial Disclosure:
    No relationships reported.

    Harold Nelson, MD
    Professor of Medicine
    Division of Allergy and Clinical Immunology
    National Jewish Health
    Denver, CO

    Financial Disclosure:
    Dr. Nelson declares that he is a consultant for Merck and investigator for Circassia.


    • Sean T. Barrett has nothing to disclose.
    • Kia K. Gray, MPH has nothing to disclose.
    • Amanda Hilferty has nothing to disclose.
    • Sarah Meadows has nothing to disclose.
    • Robert Schneider has nothing to disclose.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Discuss the pathophysiologic mechanisms of atopic dermatitis (AD)
    • Provide an update on the development of new management approaches for AD
  • Target Audience

    This activity is designed to meet the educational needs of Allergists, Immunologists, Dermatologists, Dermatology Nurses and Physician Assistants.

  • Accreditation and Credit Designation Statements

    This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of National Jewish Health and Prova Education. National Jewish Health is accredited by the ACCME to provide continuing medical education for physicians.

    National Jewish Health designates this enduring material for a maximum of .50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    This educational activity was developed in partnership with National Jewish Health and Prova Education.

    As the leading respiratory hospital in the nation for 117 years and a world class academic medical center, National Jewish Health excels at producing continuing medical education programs by creating innovative activities that assist physicians and health care providers in developing and enhancing their clinical knowledge and skills to better treat their patients. Our Mission since 1899 is to heal, to discover, and to educate as a preeminent health care institution.

    Prova Education designs educational activities based on evidence-based medicine, needs and gaps analyses, learner feedback, and more. Its mission is to serve as an innovative and relevant resource for clinical content and educational interventions across a broad spectrum of specialties.


  • Commercial Support

    This activity is supported by an independent educational grant from Sanofi US and Regeneron Pharmaceuticals.

  • Instructions

    To participate in this activity and receive credit, please follow the steps listed below. 

    Step 1: Complete the Pre-Test. This will take you to the first page of a short pre survey, which will assess your current knowledge on the subject being presented.
    Step 2: View the activity.
    Step 3: After reviewing the activity, click on the “Take Post-Test” link and complete the post-test, as well as the evaluation. You will also be asked to claim your credits and will then receive your certificate of participation.
    Step 4:  Within 45 days after the completion of this CME activity, we will send you an email requesting your participation in an online survey.  This short survey will help us evaluate how healthcare professionals have changed their clinical practice as a result of participating in this activity.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of TOPEC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Reproduction Prohibited
    Reproduction of this material is not permitted without written permission from the copyright owner.

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