ReachMD

Jane F. Apperley, MBChB, MD, FRCP, FRCPath, qualified in Medicine from the University of Birmingham in 1979. After initial specialization in internal medicine, she completed specialist training in hematology in Birmingham, London, and Cambridge. During this time, Dr. Apperley spent 2 years as a postdoctoral fellow at the Children's Hospital in Boston, where she received training in gene transfer and therapy. She was appointed as Senior Lecturer and Honorary Consultant Physician to the Hammersmith Hospital in 1993 and was later promoted to Reader (2000) and then Professor of Haemato-oncology (2002). Her particular interests are the biology and management of chronic myeloid leukemia, which has led naturally to an extensive experience in stem cell transplantation and more recently, to the use of signal transduction inhibitors in this disease. She is now the Chief of Service for Clinical Haematology at the Imperial College Healthcare National Health Service Trust and Chair of the Department of Haematology at the Imperial College. Professor Apperley is the past President of both the European Group for Blood and Marrow Transplantation and the British Society of Blood and Marrow Transplantation. She also serves on the Advisory Board of the Center for International Blood and Marrow Transplant Research. Her group at the Hammersmith Hospital site has had extensive experience in the use of the first- and second-generation tyrosine kinase inhibitors, particularly in the areas of molecular monitoring and mechanisms of drug resistance. She has a long-standing interest in the ways in which hematologic diseases and their treatment impact fertility, pregnancy, and fetal outcome.